The Dorsal Column Nuclei Scale Mechanical Sensitivity in Naive and Neuropathic Pain States
A Upadhyay, MA Gradwell, TJ Vajtay, J Conner… - bioRxiv, 2024 - biorxiv.org
… with neuronal hyperactivity during injury-induced neuropathic … retrograde tracing from the
thalamus to fluorescently label Gr … In summary, we observed an increase in c-Fos+ neurons in …
thalamus to fluorescently label Gr … In summary, we observed an increase in c-Fos+ neurons in …
Differential Activation of Pain Circuitry Neuron Populations in Spinal Cord Injury Induced Neuropathic Pain
EV Brown - 2021 - search.proquest.com
… neuronal activation post-SCI, we took advantage of the immediate early gene c-fos, which
is an established marker of neuronal … of mechanical allodynia in peripheral nerve injury, …
is an established marker of neuronal … of mechanical allodynia in peripheral nerve injury, …
Modulation of sensory processing by direct descending projections from the somatosensory cortex to the spinal dorsal horn
N Frezel - 2019 - theses.hal.science
… injury-induced mechanical hypersensitivity15. Activation of the … In mice for example, the
immediate early gene c-fos is upregulated … Using rAAV vector based retrograde tracing, we have …
immediate early gene c-fos is upregulated … Using rAAV vector based retrograde tracing, we have …
[PDF][PDF] Spinal cord retinoic acid receptor signaling gates mechanical hypersensitivity in neuropathic pain
B Cao, G Scherrer, L Chen - Neuron, 2022 - cell.com
… -injuryinduced homeostatic changes that lead to central … retrograde labeling of dorsal horn
nociceptive projection … idence that concomitant pre- and post-synaptic disinhibition of the iPV+ …
nociceptive projection … idence that concomitant pre- and post-synaptic disinhibition of the iPV+ …
[HTML][HTML] Central sensitization and neuropathic features of ongoing pain in a rat model of advanced osteoarthritis
J Havelin, I Imbert, J Cormier, J Allen, F Porreca… - The Journal of …, 2016 - Elsevier
… early oncogene, FOS, in the spinal dorsal horn. Inactivation of … pain in animals with nerve
injury–induced pain, indicating that … labeled staining was performed within the ipsilateral dorsal …
injury–induced pain, indicating that … labeled staining was performed within the ipsilateral dorsal …
[HTML][HTML] Facilitation of neuropathic pain by the NPY Y1 receptor-expressing subpopulation of excitatory interneurons in the dorsal horn
… in the dorsal horn: NPY Y1 receptors (Y1Rs) on post-synaptic … of nerve-injury induced
hyperalgesia and allodynia over … Y1R-ir cells exhibited retrograde labeling in lamina I, V, and X …
hyperalgesia and allodynia over … Y1R-ir cells exhibited retrograde labeling in lamina I, V, and X …
[HTML][HTML] Postsynaptic dorsal column pathway activation during spinal cord stimulation in patients with chronic pain
GE Gmel, R Santos Escapa, TE Benkohen… - Frontiers in …, 2023 - frontiersin.org
… SCS therapy, found that post-synaptic dorsal column (PSDC) fibres … lack of distinct qualitative
descriptions of the stimulation sensation from each patient. We did not record any marked …
descriptions of the stimulation sensation from each patient. We did not record any marked …
An inhibitory circuit from central amygdala to zona incerta drives pain-related behaviors in mice
S Singh, TD Wilson, S Valdivia, B Benowitz… - Elife, 2022 - elifesciences.org
… GABAergic ZI neurons reversed nerve injury- induced hyper… neurons to the ZI, we
stereotaxically injected the retrograde … ZI neurons also display inhibitory post- synaptic currents in …
stereotaxically injected the retrograde … ZI neurons also display inhibitory post- synaptic currents in …
Central nervous system pain pathways
AJ Todd, F Wang - The Oxford Handbook of the Neurobiology of …, 2018 - books.google.com
… Until recently, the postsynaptic targets of these “propriospinal… segment that can be retrogradely
labeled from various brain … Injury-induced mechanical hypersensitivity requires C-low …
labeled from various brain … Injury-induced mechanical hypersensitivity requires C-low …
Pregnancy suppresses neuropathic pain induced by chronic constriction injury in rats through the inhibition of TNF-α
Y Onodera, M Kanao-Kanda, H Kanda… - Journal of pain …, 2017 - Taylor & Francis
… whether nerve injury induced a glial reaction in the spinal dorsal … injury-induced tactile
allodynia is present in the absence of FOS labeling in retrogradely labeled post-synaptic dorsal …
allodynia is present in the absence of FOS labeling in retrogradely labeled post-synaptic dorsal …